SECTION 1. DIAGNOSIS, EVALUATION, AND TREATMENT OF HYPERTENSION
1. OVERVIEW OF HYPERTENSION
- Defi nition
- Incidence
- Natural History
- Etiology
- Pathophysiology
- Approach to Diagnosis and Treatment
- Effect of Treatment
- Awareness, Treatment, and Control
- Prevention
2. EVALUATION OF HYPERTENSION
Step 1. Confi rm and Stage Hypertension
- Proper Blood Pressure Measurement
- Technique
- Exclude White-Coat Hypertension and
- Pseudohypertension
- Staging Blood Pressure
- Ambulatory Blood Pressure Monitoring
Step 2. Evaluate the Patient Clinically
- Overview
- Assessment of Target Organ Damage
- Detection of Secondary Hypertension
Step 3. Risk Stratification
- Overview
- Low-Risk (Group A)
- Intermediate-Risk (Group B)
- High-Risk (Group C)
Step 4. Initiate Treatment and Optimize
- Compliance
- Blood Pressure Goals
- Approach to Treatment
- Therapeutic Lifestyle Changes
- Drug Therapy
- Optimizing Patient Compliance
3. TREATMENT OF ESSENTIAL
HYPERTENSION
4. ANTIHYPERTENSIVE DRUG
CLASSES: MECHANISM OF ACTION AND
SELECTED FEATURES
Diuretics and Potassium Sparers
- Mechanism of Action
- Major Use
- Dosage and Administration
- Frequent or Serious Adverse Effects
- Aldosterone Blockers
ACE Inhibitors
- Mechanism of Action
- Major Uses
- Administration and Monitoring
- Frequent or Severe Adverse Effects
- Angiotensin II Receptor Blockers
- Mechanism of Action
- Clinical Effects
- Administration and Side Effects
Direct Renin Inhibitors (DRI)
- β-Blockers
- Mechanism of Action
- Properties
- Major Uses
- Frequency of Serious Side Effects
Vasodilating β-Blockers
- Calcium Channel Blockers
- Mechanism of Action
- Major Uses
- Frequency of Serious Adverse Effects
α-1 Adrenergic Blockers
- Central α-Adrenergic Agents
- Direct Vasodilators
- Choices of Therapy
SECTION 2. OTHER TOPICS IN HYPERTENSION
5. HYPERTENSIVE CRISIS
6. RESISTANT HYPERTENSION
7. IDENTIFIABLE (SECONDARY)HYPERTENSION
Clinical Trials
- ACCOMPLISH
- ALLHAT
- ANBP2
- ASCOT
- CONVINCE
- DORADO
- EXFORGE-HCT
- HYVET
- INVEST
- LIFE
- ONTARGET
- TEKTURNA HCT
- VALUE
REFERENCES
INDEX
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